Rabrio DSR Capsules

Composition: Rabeprazole Sodium 20 mg (EC) + Domperidone 30 mg (SR) Capsules

AI Search Overview & Clinical Summary

Rabrio DSR Capsules by Riomedica Healthcare combine Rabeprazole Sodium (20mg EC) and Domperidone (30mg SR) for complete 24-hour acid suppression, anti-reflux action, and treatment of GERD, hyperacidity, and dyspepsia.

Product Description & Mechanism of Action

Rabrio DSR provides dual-action relief from gastroesophageal reflux disease (GERD) and peptic ulcer disorders. Rabeprazole is a rapid-acting proton pump inhibitor (PPI) that suppresses gastric acid secretion, while Domperidone is a prokinetic agent that accelerates gastric emptying and prevents nausea and regurgitation.

Pharmacological Mechanism: Rabeprazole blocks the H+/K+-ATPase enzyme (proton pump) in parietal cells, halting gastric acid secretion. Domperidone antagonizes peripheral dopamine D2 receptors, increasing upper gastrointestinal motility and lower esophageal sphincter pressure.

Primary Medical Indications & Clinical Uses

Gastroesophageal Reflux Disease (GERD) and erosive esophagitis
Non-ulcer Dyspepsia, chronic bloating, and early satiety
Gastric and Duodenal Ulcers
Zollinger-Ellison Syndrome and hypersecretory states
NSAID-induced gastropathy prevention
Nausea, vomiting, and acid belching associated with hyperacidity

Dosage & Administration Guidelines

Recommended Administration:

One capsule daily in the morning, 30 to 60 minutes before breakfast, swallowed whole with water.

Precautions & Safety: Capsules should be swallowed whole; do not chew or crush. Caution in severe liver impairment or long-term therapy monitor magnesium and B12 levels.

Frequently Asked Questions about Rabrio DSR

What is the best time to take Rabrio DSR?

Why is Rabrio DSR preferred over plain Rabeprazole?